Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14305754 | 0.88 | CYP19A1 (0.43) | CYP19A1SMN1; SMN2TSHRLMNAHTT | |
| SCHEMBL5691629 | 0.85 | TLR8 (0.42) | CYP19A1ALDH1A1KMT2A | |
| SCHEMBL5691544 | 0.85 | TLR8 (0.42) | CYP19A1ALDH1A1KMT2A | |
| SCHEMBL16267964 | 0.84 | CYP19A1 (0.47) | CYP19A1SMN1; SMN2TSHRLMNAHTT | |
| SCHEMBL585669 | 0.84 | CYP19A1 (0.43) | CYP19A1SMN1; SMN2TSHRLMNAHTT | |
| SCHEMBL27850120 | 0.83 | CYP19A1 (0.45) | CYP19A1SMN1; SMN2TSHRLMNAHTT | |
| SCHEMBL6855316 | 0.83 | CYP19A1 (0.47) | CYP19A1SMN1; SMN2TSHRLMNAHTT | |
| SCHEMBL24880321 | 0.81 | PDE10A (0.36) | CYP19A1TSHRGRM5TYRPDE10A | |
| SCHEMBL1435520 | 0.81 | CYP19A1 (0.41) | CYP19A1SMN1; SMN2TSHRLMNAHTT | |
| SCHEMBL16268174 | 0.81 | CYP19A1 (0.44) | CYP19A1SMN1; SMN2TSHRLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107365439-B | Novel chloroprene rubber vulcanization method | 华南理工大学 | 2020-02-18 | — | — | CN | claimed |
| US-5081217-A | Curable resins with low dielectric constants | SHELL OIL COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| US-4514556-A | REACTION OF 2-ETHYL-4-METHYL IMIDAZOLE WITH CATALYST AND FORMALDEHYDE OR METHYLENIZING AGENT, CURING AGENT FOR EPOXY RESIN | SHIKOKU CHEMICALS CORPORATION (JP) | 1985-04-30 | — | — | US | disclosed |
| EP-0126531-A2 | 4,4'-Methylene-bis-(2-ethyl-5-methyl imidazole) and methods of producing and using the same | SHIKOKU CHEMICALS CORPORATION (JP) | 1984-11-28 | — | — | EP | disclosed |