Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 3/20 | 0.47 |
| ▸ | MMP1 | P03956 | 3/20 | 0.42 |
| ▸ | MMP9 | P14780 | 3/20 | 0.42 |
| ▸ | MMP13 | P45452 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30114437 | 0.87 | BMP1 (0.46) | BMP1MMP1MMP9MMP13LMNA | |
| SCHEMBL28961312 | 0.87 | BMP1 (0.46) | BMP1MMP1MMP9MMP13LMNA | |
| SCHEMBL29206993 | 0.84 | BMP1 (0.47) | BMP1MMP1MMP9MMP13LMNA | |
| SCHEMBL24497433 | 0.84 | BMP1 (0.47) | BMP1MMP1MMP9MMP13LMNA | |
| SCHEMBL30876228 | 0.84 | BMP1 (0.47) | BMP1MMP1MMP9MMP13LMNA | |
| SCHEMBL29648392 | 0.81 | BMP1 (0.44) | BMP1MMP1MMP9MMP13LMNA | |
| SCHEMBL24497371 | 0.81 | BMP1 (0.44) | BMP1MMP1MMP9MMP13LMNA | |
| SCHEMBL22718052 | 0.78 | KDR (0.48) | BMP1MMP1MMP9MMP13LMNA | |
| SCHEMBL29438855 | 0.78 | KDR (0.48) | BMP1MMP1MMP9MMP13LMNA | |
| SCHEMBL24497380 | 0.78 | LMNA (0.44) | MMP9MMP13LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594680-A | TEAD inhibitor | 武汉人福创新药物研发中心有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| WO-2023280254-A1 | TEAD INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2023-01-12 | — | — | WO | disclosed |
| WO-2023280254-A1 | TEAD INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2023-01-12 | — | — | WO | disclosed |