Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 7/20 | 0.47 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.43 |
| ▸ | IKZF2 | Q9UKS7 | 11/20 | 0.40 |
| ▸ | WIZ | O95785 | 2/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.36 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL27216591 | 0.88 | CRBN (0.49) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL24880474 | 0.88 | CRBN (0.48) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL30080867 | 0.80 | CRBN (0.42) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL27216611 | 0.80 | CRBN (0.42) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL27216586 | 0.78 | GSPT1 (0.37) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL24571664 | 0.76 | CRBN (0.52) | CRBNGSPT1DDB1IKZF3IKZF2 | |
| SCHEMBL30984991 | 0.76 | CRBN (0.51) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL4450784 | 0.74 | CRBN (0.60) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL30984958 | 0.74 | CRBN (0.51) | CRBNGSPT1DDB1IKZF3IKZF2 | |
| SCHEMBL31554603 | 0.74 | CRBN (0.56) | CRBNGSPT1DDB1CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280237-A1 | SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER | 海创药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |