Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.42 |
| ▸ | IKZF2 | Q9UKS7 | 7/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.37 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.37 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27216611 | 1.00 | CRBN (0.42) | CRBNIKZF2CSNK1A1DDB1GSPT1 | |
| SCHEMBL24880497 | 0.88 | CRBN (0.47) | CRBNIKZF2CSNK1A1 | |
| Hydrochloric Acid SCHEMBL27216595 | 0.85 | CRBN (0.46) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL30080888 | 0.82 | CRBN (0.41) | CRBNIKZF2CSNK1A1DDB1GSPT1 | |
| SCHEMBL24571664 | 0.81 | CRBN (0.52) | CRBNIKZF2CSNK1A1DDB1GSPT1 | |
| SCHEMBL30984991 | 0.80 | CRBN (0.51) | CRBNIKZF2CSNK1A1DDB1GSPT1 | |
| SCHEMBL24880604 | 0.80 | CRBN (0.47) | CRBNIKZF2CSNK1A1DDB1GSPT1 | |
| SCHEMBL31158803 | 0.79 | CRBN (0.51) | CRBNIKZF2CSNK1A1DDB1GSPT1 | |
| SCHEMBL30984958 | 0.79 | CRBN (0.51) | CRBNIKZF2CSNK1A1DDB1GSPT1 | |
| SCHEMBL27216583 | 0.78 | CRBN (0.44) | CRBNIKZF2CSNK1A1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594666-B | Synthesis and application of phosphatase degradation agent | 海创药业股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-115594666-A | Synthesis and application of phosphatase degrading agent | 海创药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |