Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 18/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 16/20 | 0.36 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30112373 | 0.85 | CRBN (0.39) | POLBCRBNDDB1 | |
| SCHEMBL24880669 | 0.85 | CRBN (0.39) | POLBCRBNDDB1 | |
| SCHEMBL24880668 | 0.81 | DDB1 (0.50) | CRBNDDB1 | |
| SCHEMBL30112339 | 0.81 | DDB1 (0.50) | CRBNDDB1 | |
| SCHEMBL24881066 | 0.80 | CRBN (0.43) | CRBNDDB1 | |
| SCHEMBL31583448 | 0.80 | CRBN (0.43) | CRBNDDB1 | |
| SCHEMBL24880882 | 0.80 | POLB (0.34) | POLBCRBNDDB1 | |
| SCHEMBL24880619 | 0.80 | POLB (0.34) | POLBCRBNDDB1 | |
| SCHEMBL24881292 | 0.79 | CRBN (0.44) | POLBCRBNDDB1 | |
| Hydrochloric Acid SCHEMBL31583577 | 0.79 | CRBN (0.43) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283610-A1 | COMPOUNDS FOR TARGETING DEGRADATION OF IRAK4 PROTEINS | BIOGEN MA INC. (US) | 2023-01-12 | — | — | WO | disclosed |