SCHEMBL24880754

SCHEMBL24880754

COC1CCN(c2ncc(C(=O)O)cn2)CC1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.56
AOC3 Q16853 2/20 0.49
SCD O00767 1/20 0.44
PTGER4 P35408 1/20 0.44
KDM4E B2RXH2 2/20 0.43
HRH3 Q9Y5N1 1/20 0.43
CYP2C19 P33261 1/20 0.43
OGA O60502 1/20 0.43
KCNQ3 O43525 5/20 0.41
KCNQ2 O43526 5/20 0.41
KCNQ4 P56696 1/20 0.41
KCNQ5 Q9NR82 1/20 0.41
DGAT2 Q96PD7 1/20 0.40
KDM1A O60341 1/20 0.40
ACACB O00763 2/20 0.39
MAPT P10636 1/20 0.39
ADRA1A P35348 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2189524 0.90 AOC3 (0.50) POLBAOC3HRH3DGAT2ACACB
SCHEMBL20148210 0.87 AOC3 (0.51) POLBAOC3HRH3KCNQ3KCNQ2
SCHEMBL2191078 0.84 POLB (0.51) POLBAOC3KDM4EOGAKCNQ3
SCHEMBL1270475 0.83 POLB (0.61) POLBKDM4ECYP2C19OGAKDM1A
SCHEMBL24880446 0.82 HRH3 (0.47) POLBAOC3HRH3OGAKCNQ3
SCHEMBL14575817 0.81 HRH3 (0.63) SCDPTGER4HRH3ADRA1A
SCHEMBL31104582 0.81 AOC3 (0.53) AOC3KDM4ECYP2C19KCNQ3KCNQ2
SCHEMBL22692228 0.79 POLB (0.50) POLBKDM4EKDM1A
SCHEMBL17411280 0.79 AOC3 (0.51) AOC3SCDOGA
SCHEMBL15341332 0.79 POLB (0.56) POLBKDM4ECYP2C19OGAKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023280237-A1 SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER 海创药业股份有限公司 2023-01-12 WO disclosed