Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.40 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24880754 | 0.87 | POLB (0.56) | AOC3HRH3POLBMAPTKCNQ3 | |
| SCHEMBL30754057 | 0.82 | HRH3 (0.64) | HRH3 | |
| SCHEMBL24880446 | 0.81 | HRH3 (0.47) | AOC3HRH3POLBMAPTKCNQ3 | |
| SCHEMBL31104582 | 0.80 | AOC3 (0.53) | AOC3EGFRKCNQ3KCNQ2KCNQ4 | |
| SCHEMBL24126684 | 0.79 | HRH3 (0.44) | HRH3POLBMAPT | |
| Hydrochloric Acid SCHEMBL27796614 | 0.78 | HRH3 (0.43) | HRH3POLB | |
| SCHEMBL17411280 | 0.78 | AOC3 (0.51) | AOC3EGFR | |
| SCHEMBL30588209 | 0.78 | MAPK8 (0.45) | HRH3POLB | |
| SCHEMBL20917117 | 0.77 | POLB (0.50) | AOC3POLBMAPT | |
| Hydrochloric Acid SCHEMBL2189524 | 0.77 | AOC3 (0.50) | AOC3HRH3POLBDGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134688-A1 | NOVEL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134688-A1 | NOVEL COMPOUNDS | RIPK2, RIPK1, RIPK4 | AOC3 4660/4885HRH3 3405/4885EGFR 3844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.