Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 9/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | ELOC | Q15369 | 3/20 | 0.33 |
| ▸ | ELOB | Q15370 | 3/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23880997 | 0.83 | VHL (0.60) | VHLKDM4EPKMPIK3CDPIK3CA | |
| SCHEMBL19600685 | 0.78 | VHL (0.54) | VHLKDM4EPKMELOCELOB | |
| SCHEMBL19661678 | 0.77 | VHL (0.53) | VHLKDM4EPKMELOCELOB | |
| SCHEMBL25473160 | 0.75 | VHL (0.49) | VHLKDM4EPKMPIK3CDPIK3CA | |
| SCHEMBL24440459 | 0.75 | VHL (0.51) | VHLKDM4EPKMELOCELOB | |
| SCHEMBL23037352 | 0.74 | VHL (0.51) | VHLKDM4EPKMELOCELOB | |
| SCHEMBL22130274 | 0.74 | VHL (0.50) | VHLKDM4EPKMELOCELOB | |
| SCHEMBL26132897 | 0.74 | VHL (0.61) | VHLELOCELOB | |
| SCHEMBL23037321 | 0.72 | ALDH1A1 (0.45) | VHLKDM4EELOCELOBP2RX3 | |
| SCHEMBL23478765 | 0.71 | VHL (0.48) | VHLKDM4EELOCELOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280237-A1 | SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER | 海创药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |