Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16244656 | 0.90 | SMN1; SMN2 (0.45) | KMT2ASMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL25399863 | 0.88 | KMT2A (0.46) | KMT2ASMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL9681221 | 0.88 | KMT2A (0.44) | KMT2ASMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL16344633 | 0.86 | KMT2A (0.48) | KMT2ASMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL24880478 | 0.84 | PLAT (0.44) | KMT2ASMN1; SMN2SLC6A4 | |
| SCHEMBL18394940 | 0.84 | KCNJ6 (0.44) | KMT2ASMN1; SMN2ALDH1A1LMNAALOX15 | |
| Hydrochloric Acid SCHEMBL27216607 | 0.83 | PLAT (0.43) | KMT2ASMN1; SMN2SLC6A4 | |
| SCHEMBL24880479 | 0.82 | GPR119 (0.46) | KMT2ASMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL24880480 | 0.82 | KDM4E (0.38) | KMT2ASMN1; SMN2ALDH1A1KCNH2 | |
| SCHEMBL20944278 | 0.81 | KMT2A (0.40) | KMT2ASMN1; SMN2RAB9AALDH1A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280237-A1 | SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER | 海创药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |