SCHEMBL25399863

SCHEMBL25399863

CCOC(=O)c1cc(C)nn1C1CCCC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 6/20 0.44
MAPK1 P28482 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
PDE7A Q13946 2/20 0.43
TSHR P16473 1/20 0.43
KCNJ6 P48051 4/20 0.43
KCNJ3 P48549 4/20 0.43
KCNJ5 P48544 3/20 0.43
POLB P06746 1/20 0.43
NR2F2 P24468 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
MAPT P10636 2/20 0.42
KDM4E B2RXH2 1/20 0.42
FAAH O00519 2/20 0.41
LMNA P02545 2/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
S1PR2 O95136 1/20 0.41
XBP1 P17861 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16344633 0.99 KMT2A (0.48) KMT2AALDH1A1MAPK1SMN1; SMN2PDE7A
SCHEMBL9681221 0.97 KMT2A (0.44) KMT2AALDH1A1MAPK1SMN1; SMN2PDE7A
SCHEMBL16244656 0.94 SMN1; SMN2 (0.45) KMT2AALDH1A1MAPK1SMN1; SMN2PDE7A
SCHEMBL18394940 0.88 KCNJ6 (0.44) KMT2AALDH1A1SMN1; SMN2KCNJ6KCNJ3
SCHEMBL24880957 0.88 KMT2A (0.42) KMT2AALDH1A1SMN1; SMN2POLBFAAH
SCHEMBL24880478 0.88 PLAT (0.44) KMT2ASMN1; SMN2KDM4E
Hydrochloric Acid SCHEMBL27216607 0.87 PLAT (0.43) KMT2ASMN1; SMN2KDM4E
SCHEMBL20944278 0.81 KMT2A (0.40) KMT2AALDH1A1MAPK1SMN1; SMN2PDE7A
SCHEMBL24880479 0.81 GPR119 (0.46) KMT2AALDH1A1SMN1; SMN2POLBNPSR1
SCHEMBL25400204 0.80 KCNJ3 (0.45) ALDH1A1KCNJ6KCNJ3KCNJ5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570675-B2 Boronic acid compounds LG CHEM, LTD. (KR) 2026-03-10 US disclosed
US-20240101579-A1 BORONIC ACID COMPOUNDS LG CHEM, LTD. (KR) 2024-03-28 US disclosed
EP-4242213-A1 BORONIC ACID COMPOUND Lg Chem, Ltd. (KR) 2023-09-13 EP disclosed
CN-116568310-A Boric acid compounds 株式会社LG化学 2023-08-08 CN disclosed
WO-2022123530-A1 BORONIC ACID COMPOUND 주식회사 엘지화학 2022-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570675-B2 Boronic acid compounds PSMB6, PSMB3, PSMB2 KMT2A 2072/4885ALDH1A1 3621/4885MAPK1 815/4885
US-20240101579-A1 BORONIC ACID COMPOUNDS PSMB11, PSMB1, BACH1 KMT2A 1197/4885ALDH1A1 2005/4885MAPK1 152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.