Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 7/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | YAP1 | P46937 | 2/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29196995 | 0.88 | ALOX5AP (0.41) | PRMT5GPR119STSYAP1 | |
| SCHEMBL24206930 | 0.87 | PRMT5 (0.52) | PRMT5GPR119STSYAP1P2RY14 | |
| SCHEMBL31281916 | 0.85 | DGAT2 (0.36) | PRMT5GPR119STSYAP1P2RY14 | |
| SCHEMBL16874565 | 0.84 | YAP1 (0.52) | PRMT5GPR119STSYAP1 | |
| SCHEMBL30830984 | 0.83 | PRMT5 (0.45) | PRMT5GPR119 | |
| SCHEMBL31232761 | 0.83 | PRMT5 (0.54) | PRMT5GPR119 | |
| SCHEMBL30768467 | 0.83 | PRMT5 (0.43) | PRMT5GPR119 | |
| SCHEMBL29223506 | 0.82 | PRMT5 (0.53) | PRMT5GPR119YAP1 | |
| SCHEMBL30796702 | 0.82 | STS (0.40) | PRMT5GPR119STSYAP1 | |
| SCHEMBL27449597 | 0.82 | STS (0.40) | PRMT5GPR119STSYAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283610-A1 | COMPOUNDS FOR TARGETING DEGRADATION OF IRAK4 PROTEINS | BIOGEN MA INC. (US) | 2023-01-12 | — | — | WO | disclosed |