Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30112328 | 1.00 | LMNA (0.51) | LMNAPGRMAOBBRD4DAO | |
| SCHEMBL15651338 | 0.85 | LMNA (0.53) | LMNAPGRMAOBBRD4DAO | |
| SCHEMBL7220153 | 0.77 | LMNA (0.56) | LMNAPGRMAOBBRD4DAO | |
| SCHEMBL7220155 | 0.75 | DAO (0.66) | LMNAPGRMAOBBRD4DAO | |
| SCHEMBL2522765 | 0.75 | LMNA (0.58) | LMNAPGRMAOBBRD4DAO | |
| SCHEMBL29859942 | 0.75 | LMNA (0.58) | LMNAPGRMAOBBRD4DAO | |
| SCHEMBL12647229 | 0.75 | LMNA (0.46) | LMNAPGRMAOBBRD4DAO | |
| SCHEMBL12838121 | 0.74 | LMNA (0.56) | LMNAPGRMAOBBRD4DAO | |
| SCHEMBL1519715 | 0.74 | LMNA (0.56) | LMNAPGRMAOBBRD4DAO | |
| SCHEMBL6770061 | 0.74 | DAO (0.64) | LMNAPGRMAOBBRD4DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283610-A1 | COMPOUNDS FOR TARGETING DEGRADATION OF IRAK4 PROTEINS | BIOGEN MA INC. (US) | 2023-01-12 | — | — | WO | disclosed |