⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24883100 | 0.81 | — | — | |
| SCHEMBL24883105 | 0.78 | — | — | |
| SCHEMBL26886742 | 0.78 | ALDH1A1 (0.35) | — | |
| SCHEMBL21736607 | 0.75 | APLNR (0.31) | — | |
| SCHEMBL24354653 | 0.75 | APLNR (0.31) | — | |
| SCHEMBL20757585 | 0.74 | EPHX2 (0.30) | — | |
| SCHEMBL24527146 | 0.70 | — | — | |
| SCHEMBL24538367 | 0.67 | ALDH1A1 (0.44) | — | |
| SCHEMBL20031091 | 0.67 | — | — | |
| SCHEMBL24538449 | 0.67 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283430-A1 | CYCLOALKYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT MODULATE IKZF2 | Plexium, Inc. (US) | 2023-01-12 | — | — | WO | disclosed |