Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24883387 | 0.98 | OPRK1 (0.36) | OPRK1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL12409015 | 0.81 | HRH3 (0.34) | OPRK1KMT2ANPC1RAB9AHRH3 | |
| SCHEMBL17665915 | 0.79 | HRH3 (0.36) | KMT2ANPC1RAB9AHRH3 | |
| SCHEMBL26619666 | 0.76 | IRAK4 (0.35) | HRH3 | |
| SCHEMBL26823952 | 0.76 | HRH3 (0.34) | KMT2ANPC1RAB9AHRH3 | |
| SCHEMBL10589619 | 0.75 | ALDH1A1 (0.44) | — | |
| SCHEMBL15382240 | 0.75 | ALDH1A1 (0.44) | — | |
| SCHEMBL10589624 | 0.75 | ALDH1A1 (0.44) | — | |
| SCHEMBL4547601 | 0.75 | EPHX2 (0.31) | — | |
| SCHEMBL1825076 | 0.74 | HRH3 (0.42) | KMT2ANPC1RAB9AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283430-A1 | CYCLOALKYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT MODULATE IKZF2 | Plexium, Inc. (US) | 2023-01-12 | — | — | WO | disclosed |