Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 6/20 | 0.47 |
| ▸ | KDR | P35968 | 9/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 2/20 | 0.37 |
| ▸ | RIPK3 | Q9Y572 | 4/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.35 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24885740 | 0.95 | BRAF (0.47) | BRAFKDRPDGFRBKITFLT1 | |
| SCHEMBL24885912 | 0.87 | BRAF (0.46) | BRAFKDRPDGFRBKITFLT1 | |
| SCHEMBL24885416 | 0.75 | BRAF (0.45) | BRAFMAPK14KDM4EALDH1A1HPGD | |
| SCHEMBL24885915 | 0.74 | BRAF (0.55) | BRAFKDRPDGFRBKITFLT1 | |
| SCHEMBL30078242 | 0.70 | ABL1 (0.53) | BRAFKDRPDGFRBKITFLT1 | |
| SCHEMBL24885734 | 0.70 | ABL1 (0.53) | BRAFKDRPDGFRBKITFLT1 | |
| SCHEMBL2851409 | 0.70 | BRAF (0.62) | BRAFKDRPDGFRBKITFLT1 | |
| SCHEMBL24885518 | 0.68 | BRAF (0.47) | BRAFKDRPDGFRBKITFLT1 | |
| SCHEMBL31290967 | 0.68 | BRAF (0.47) | BRAFKDRPDGFRBKITFLT1 | |
| SCHEMBL24885523 | 0.67 | AXL (0.63) | KDRKITPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400577-A1 | MODULATORS OF PROTEIN KINASES | VIBLIOME THERAPEUTICS, LLC | 2024-12-05 | — | — | US | disclosed |
| WO-2023283369-A1 | MODULATORS OF PROTEIN KINASES | VIBLIOME THERAPEUTICS, LLC (US) | 2023-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400577-A1 | MODULATORS OF PROTEIN KINASES | MAP3K20, PRKCE, PRKCH | BRAF 141/4885KDR 973/4885PDGFRB 750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.