SCHEMBL2488720

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2494381	0.98	CYP2B6 (0.44)	TSHRCYP2B6HRH3MEN1KMT2A
	SCHEMBL2489520	0.90	CYP2B6 (0.56)	TSHRCYP2B6HRH3MEN1KMT2A
	SCHEMBL12199488	0.90	CYP2B6 (0.56)	TSHRCYP2B6HRH3MEN1KMT2A
	SCHEMBL12199483	0.86	ACHE (0.50)	HRH3MEN1KMT2AALDH1A1ACHE
	SCHEMBL12225851	0.86	ACHE (0.50)	HRH3MEN1KMT2AALDH1A1ACHE
	SCHEMBL2488565	0.81	ADRB1 (0.52)	TSHRALDH1A1HPGD
	SCHEMBL12199479	0.80	CYP2B6 (0.46)	CYP2B6MEN1KMT2AALDH1A1ACHE
	SCHEMBL8354616	0.80	CYP2B6 (0.64)	TSHRCYP2B6HRH3MEN1KMT2A
	SCHEMBL8354397	0.78	CYP2B6 (0.68)	TSHRCYP2B6HRH3MEN1KMT2A
	SCHEMBL2489523	0.77	ESR1 (0.41)	TSHRCYP2B6MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.