Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3851252 | 0.85 | GRM2 (0.63) | SIRT1GRM2 | |
| SCHEMBL2853554 | 0.82 | GRM2 (0.69) | SIRT1GRM2 | |
| SCHEMBL13359773 | 0.80 | GRM2 (0.64) | GRM2 | |
| SCHEMBL24890846 | 0.80 | HDAC1 (0.48) | SIRT1GRM2FAAHMEN1KMT2A | |
| SCHEMBL24890867 | 0.80 | GRM2 (0.69) | GRM2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2832784 | 0.78 | GRM2 (0.54) | SIRT1GRM2MAPK1 | |
| SCHEMBL2901624 | 0.78 | FADS1 (0.53) | SIRT1GRM2MEN1KMT2AMAPK1 | |
| SCHEMBL14687126 | 0.74 | MAPK1 (0.51) | SIRT1LOXL2GRM2FAAHKDM4E | |
| SCHEMBL2414084 | 0.73 | POLB (0.56) | SIRT1LOXL2FAAHMEN1KMT2A | |
| SCHEMBL20524383 | 0.73 | GRM2 (0.64) | SIRT1GRM2SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284651-A1 | N-(2-AMINOPHENYL)BENZAMIDE COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2023-01-19 | — | — | WO | disclosed |