Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24890849 | 0.80 | SIRT1 (0.56) | HDAC1HDAC6SIRT1SIRT2FAAH | |
| SCHEMBL3851252 | 0.77 | GRM2 (0.63) | SIRT1GRM2 | |
| SCHEMBL2853554 | 0.75 | GRM2 (0.69) | SIRT1GRM2 | |
| SCHEMBL24073240 | 0.72 | HDAC1 (0.52) | HDAC1HDAC6SIRT1SIRT2KMT2A | |
| SCHEMBL17107915 | 0.72 | GAA (0.34) | RORC | |
| SCHEMBL1206337 | 0.71 | NAMPT (0.55) | HDAC1MEN1KMT2ANPC1LMNA | |
| SCHEMBL2901624 | 0.71 | FADS1 (0.53) | SIRT1GRM2MEN1KMT2AMAPK1 | |
| SCHEMBL14197146 | 0.70 | MAOB (0.46) | LMNA | |
| SCHEMBL31165348 | 0.70 | NPFFR1 (0.49) | KMT2A | |
| SCHEMBL15647055 | 0.69 | LOXL2 (0.49) | HDAC1HDAC6MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284651-A1 | N-(2-AMINOPHENYL)BENZAMIDE COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2023-01-19 | — | — | WO | disclosed |