Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.63 |
| ▸ | CDK7 | P50613 | 1/20 | 0.47 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.47 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.47 |
| ▸ | WNT3A | P56704 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.44 |
| ▸ | GRM5 | P41594 | 5/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891783 | 0.90 | NAMPT (0.57) | NAMPTCDK7CDK13CDK12WNT3A | |
| SCHEMBL24892373 | 0.89 | NAMPT (0.55) | NAMPTCDK7CDK13CDK12WNT3A | |
| SCHEMBL24891865 | 0.87 | NAMPT (0.55) | NAMPTCDK7CDK13CDK12WNT3A | |
| SCHEMBL24891878 | 0.85 | NAMPT (0.51) | NAMPTCDK7CDK13CDK12WNT3A | |
| SCHEMBL24891670 | 0.84 | NAMPT (0.57) | NAMPTCDK7CDK13CDK12WNT3A | |
| SCHEMBL24891972 | 0.84 | NAMPT (0.51) | NAMPTCDK7CDK13CDK12WNT3A | |
| SCHEMBL30182359 | 0.84 | NAMPT (0.51) | NAMPTCDK7CDK13CDK12WNT3A | |
| SCHEMBL24892192 | 0.84 | NAMPT (0.51) | NAMPTCDK7CDK13CDK12WNT3A | |
| SCHEMBL22325022 | 0.83 | NAMPT (0.71) | NAMPTCDK7CDK13CDK12WNT3A | |
| SCHEMBL24891933 | 0.83 | NAMPT (0.55) | NAMPTCDK7CDK13CDK12WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |