Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.41 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 5/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 4/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.40 |
| ▸ | LIPC | P11150 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30182359 | 1.00 | NAMPT (0.51) | NAMPTTLR7DGAT2WNT3ACDK7 | |
| SCHEMBL24891783 | 0.88 | NAMPT (0.57) | NAMPTDGAT2WNT3ACDK7CDK13 | |
| SCHEMBL24891865 | 0.85 | NAMPT (0.55) | NAMPTDGAT2WNT3ACDK7CDK13 | |
| SCHEMBL24891745 | 0.84 | NAMPT (0.40) | NAMPTTLR7DGAT2WNT3AKIT | |
| SCHEMBL30182708 | 0.84 | NAMPT (0.40) | NAMPTTLR7DGAT2WNT3AKIT | |
| SCHEMBL24891722 | 0.84 | NAMPT (0.63) | NAMPTWNT3ACDK7CDK13CDK12 | |
| SCHEMBL24892373 | 0.83 | NAMPT (0.55) | NAMPTDGAT2WNT3ACDK7CDK13 | |
| SCHEMBL24891670 | 0.83 | NAMPT (0.57) | NAMPTDGAT2WNT3ACDK7CDK13 | |
| SCHEMBL24891878 | 0.83 | NAMPT (0.51) | NAMPTDGAT2WNT3ACDK7CDK13 | |
| SCHEMBL24891715 | 0.82 | NAMPT (0.45) | NAMPTDGAT2WNT3AKITMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |