Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.52 |
| ▸ | FPR3 | P25089 | 2/20 | 0.52 |
| ▸ | FPR2 | P25090 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23899184 | 0.92 | NAMPT (0.59) | NAMPTFPR3FPR2KMT2ALMNA | |
| SCHEMBL30182404 | 0.92 | NAMPT (0.59) | NAMPTFPR3FPR2KMT2ALMNA | |
| SCHEMBL30182518 | 0.92 | NAMPT (0.59) | NAMPTFPR3FPR2KMT2ALMNA | |
| SCHEMBL23899088 | 0.82 | NAMPT (0.53) | NAMPTFPR3FPR2KMT2ALMNA | |
| SCHEMBL2584476 | 0.82 | ALDH1A1 (0.53) | NAMPTFPR3FPR2LMNARAB9A | |
| SCHEMBL2579030 | 0.79 | NAMPT (0.58) | NAMPTFPR3FPR2KMT2AMEN1 | |
| SCHEMBL2579027 | 0.79 | NAMPT (0.58) | NAMPTFPR3FPR2KMT2AMEN1 | |
| SCHEMBL24891649 | 0.78 | PTPN2 (0.47) | NAMPTFPR3FPR2KMT2ALMNA | |
| SCHEMBL30182272 | 0.78 | PTPN2 (0.47) | NAMPTFPR3FPR2KMT2ALMNA | |
| SCHEMBL23898940 | 0.78 | PTPN1 (0.62) | NAMPTKMT2ALMNAMEN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |