SCHEMBL2584476

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30182518	0.89	NAMPT (0.59)	LMNANAMPTFPR3FPR2L3MBTL1
	SCHEMBL30182404	0.89	NAMPT (0.59)	LMNANAMPTFPR3FPR2L3MBTL1
	SCHEMBL23899184	0.89	NAMPT (0.59)	LMNANAMPTFPR3FPR2L3MBTL1
	SCHEMBL23899088	0.89	NAMPT (0.53)	ALDH1A1LMNASMN1; SMN2HPGDUSP2
	SCHEMBL13741883	0.86	KMT2A (0.56)	ALDH1A1HPGDPKM
	SCHEMBL3180689	0.86	L3MBTL1 (0.61)	NAMPTFPR3FPR2L3MBTL1GAA
	SCHEMBL7769975	0.82	ALDH1A1 (0.56)	ALDH1A1LMNASMN1; SMN2HPGDUSP2
	SCHEMBL7773979	0.82	GLS (0.45)	ALDH1A1HPGDUSP2NPC1PKM
	SCHEMBL24891725	0.82	NAMPT (0.52)	ALDH1A1LMNANAMPTFPR3FPR2
	SCHEMBL7773978	0.82	GLS (0.45)	ALDH1A1HPGDUSP2NPC1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.