Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | UBE2N | P61088 | 1/20 | 0.57 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30182362 | 1.00 | KMT2A (0.62) | KMT2AMEN1ATMRAB9AUSP28 | |
| SCHEMBL30182624 | 0.86 | MAPT (0.64) | KMT2AMEN1ATMRAB9ANPC1 | |
| SCHEMBL24892280 | 0.86 | MAPT (0.64) | KMT2AMEN1ATMRAB9ANPC1 | |
| SCHEMBL24891755 | 0.85 | ITGB3 (0.52) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL24891825 | 0.84 | RAB9A (0.64) | KMT2AMEN1ATMRAB9ANPC1 | |
| SCHEMBL1999202 | 0.83 | MAPKAPK2 (0.65) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2000045 | 0.82 | MAPKAPK2 (0.64) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL24891707 | 0.82 | NPC1 (0.64) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL24891918 | 0.81 | KMT2A (0.58) | KMT2AMEN1ATMRAB9ANPC1 | |
| SCHEMBL30181082 | 0.81 | KMT2A (0.58) | KMT2AMEN1ATMRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |