Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | QDPR | P09417 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24892287 | 0.81 | CCNT1 (0.46) | NPC1RAB9AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL24669441 | 0.75 | TMPRSS2 (0.53) | NPC1RAB9AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL24669410 | 0.74 | NAMPT (0.55) | NPC1RAB9AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL7480803 | 0.73 | SLC6A4 (0.68) | NOS3NOS1SLC6A4 | |
| SCHEMBL8585591 | 0.72 | MEN1 (0.72) | RAB9AALDH1A1TP53SMN1; SMN2HTR1D | |
| SCHEMBL24670178 | 0.72 | TMPRSS2 (0.52) | NPC1RAB9AHTR1DMCHR1MAPT | |
| SCHEMBL24670865 | 0.71 | TMPRSS2 (0.52) | NPC1RAB9ATP53SMN1; SMN2MAPT | |
| SCHEMBL29803211 | 0.71 | TMPRSS2 (0.51) | NPC1RAB9AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL24671177 | 0.71 | TMPRSS2 (0.51) | NPC1RAB9AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL24670912 | 0.71 | NAMPT (0.49) | HTR1DMCHR1MAPTTMPRSS2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |