Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ESRRG | P62508 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30182563 | 0.90 | HDAC3 (0.46) | TP53MEN1KMT2ANPC1RAB9A | |
| SCHEMBL24891741 | 0.81 | MEN1 (0.63) | TP53MEN1KMT2ANPC1RAB9A | |
| SCHEMBL24892106 | 0.80 | ALDH1A1 (0.46) | TP53MEN1KMT2ANPC1RAB9A | |
| SCHEMBL26712085 | 0.78 | TAAR1 (0.50) | KMT2ARAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL19668154 | 0.77 | HTR6 (0.49) | KMT2AALDH1A1KDM4ESMN1; SMN2TDP1 | |
| SCHEMBL12569387 | 0.77 | PEPD (0.55) | MEN1KMT2ANPC1LMNAMAPT | |
| SCHEMBL8185226 | 0.77 | MEN1 (0.62) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL15651884 | 0.77 | POLB (0.73) | TP53MEN1KMT2ANPC1RAB9A | |
| SCHEMBL24670336 | 0.75 | TRPV1 (0.57) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL1469234 | 0.75 | AOC3 (0.59) | MEN1KMT2ARAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |