Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.51 |
| ▸ | RAB9A | P51151 | 12/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891896 | 0.83 | MAPT (0.50) | NPC1RAB9AMAPTSMN1; SMN2HTT | |
| SCHEMBL30180906 | 0.83 | MAPT (0.50) | NPC1RAB9AMAPTSMN1; SMN2HTT | |
| SCHEMBL24891720 | 0.82 | MAPKAPK2 (0.55) | NPC1RAB9AMAPTSMN1; SMN2HTT | |
| SCHEMBL16605353 | 0.78 | MCHR1 (0.54) | NPC1RAB9AMAPTSMN1; SMN2HTT | |
| Trifluoroacetic Acid SCHEMBL30182366 | 0.77 | SLC2A1 (0.49) | NPC1RAB9AMAPTSMN1; SMN2HTT | |
| Trifluoroacetic Acid SCHEMBL30182372 | 0.76 | CCNC (0.52) | NPC1RAB9AMAPTSMN1; SMN2HTT | |
| SCHEMBL24892211 | 0.72 | NPC1 (0.61) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL30182396 | 0.72 | NPC1 (0.61) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL16605355 | 0.69 | RAB9A (0.61) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL24891987 | 0.69 | ALDH1A1 (0.50) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |