Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 11/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30182338 | 0.93 | SLC2A1 (0.44) | CHIAMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24891988 | 0.83 | MAPKAPK2 (0.57) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL24892344 | 0.81 | CHIA (0.51) | CHIAMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24891879 | 0.81 | MAPT (0.64) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24669978 | 0.81 | MAPT (0.64) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24892136 | 0.80 | ACR (0.39) | KMT2AMEN1 | |
| SCHEMBL24891896 | 0.78 | MAPT (0.50) | CHIAMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30180906 | 0.78 | MAPT (0.50) | CHIAMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24891758 | 0.77 | MAPT (0.57) | CHIAMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30181019 | 0.77 | MAPT (0.57) | CHIAMAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | claimed |
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |