Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 2/20 | 0.55 |
| ▸ | FPR2 | P25090 | 2/20 | 0.55 |
| ▸ | NAMPT | P43490 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23898926 | 0.94 | NAMPT (0.57) | FPR3FPR2NAMPTMAPTTDP1 | |
| SCHEMBL24891759 | 0.91 | NAMPT (0.53) | FPR3FPR2NAMPTMAPTTDP1 | |
| SCHEMBL30182363 | 0.91 | NAMPT (0.53) | FPR3FPR2NAMPTMAPTTDP1 | |
| SCHEMBL24670224 | 0.88 | NAMPT (0.65) | FPR3FPR2NAMPTMAPTTDP1 | |
| SCHEMBL24891860 | 0.88 | NAMPT (0.65) | FPR3FPR2NAMPTMAPTTDP1 | |
| SCHEMBL30182158 | 0.85 | NAMPT (0.58) | FPR3FPR2NAMPTMAPTTDP1 | |
| SCHEMBL24891917 | 0.85 | NAMPT (0.58) | FPR3FPR2NAMPTMAPTTDP1 | |
| SCHEMBL23898942 | 0.84 | HDAC1 (0.56) | NAMPTMAPTTDP1HDAC1HDAC6 | |
| SCHEMBL81094 | 0.83 | FPR3 (0.58) | FPR3FPR2NAMPTMAPTTDP1 | |
| SCHEMBL24891826 | 0.82 | NAMPT (0.58) | FPR3FPR2NAMPTMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |