Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 2/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24892310 | 1.00 | MAPKAPK2 (0.48) | MAPKAPK2NAMPTPLAUKLKB1PLG | |
| SCHEMBL24892281 | 0.90 | MAPKAPK2 (0.56) | MAPKAPK2NAMPTPLAUKLKB1PLG | |
| SCHEMBL29803255 | 0.90 | MAPKAPK2 (0.56) | MAPKAPK2NAMPTPLAUKLKB1PLG | |
| SCHEMBL24670579 | 0.83 | QDPR (0.51) | MAPKAPK2NAMPTMLNR | |
| SCHEMBL30182365 | 0.81 | MAPKAPK2 (0.48) | MAPKAPK2NAMPTPLAUKLKB1PLG | |
| SCHEMBL24891804 | 0.81 | MAPKAPK2 (0.48) | MAPKAPK2NAMPTPLAUKLKB1PLG | |
| SCHEMBL29803788 | 0.81 | MAPKAPK2 (0.54) | MAPKAPK2NAMPTPLAUNPC1RAB9A | |
| SCHEMBL30182510 | 0.81 | MAPKAPK2 (0.52) | MAPKAPK2NAMPTPLAUKLKB1PLG | |
| SCHEMBL24892041 | 0.81 | MAPKAPK2 (0.52) | MAPKAPK2NAMPTPLAUKLKB1PLG | |
| SCHEMBL24670573 | 0.80 | MAPKAPK2 (0.59) | MAPKAPK2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |