Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.64 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | GPR183 | P32249 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ME2 | P23368 | 1/20 | 0.55 |
| ▸ | ME1 | P48163 | 1/20 | 0.55 |
| ▸ | ME3 | Q16798 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10721826 | 0.84 | MEN1 (1.00) | MEN1KMT2ALMNAUSP2GAA | |
| SCHEMBL4456981 | 0.82 | KMT2A (0.89) | MEN1KMT2ALMNAGAAALDH1A1 | |
| SCHEMBL16599447 | 0.82 | KMT2A (0.89) | MEN1KMT2ALMNAGAAALDH1A1 | |
| SCHEMBL16599448 | 0.82 | KMT2A (0.89) | MEN1KMT2ALMNAGAAALDH1A1 | |
| SCHEMBL16333072 | 0.78 | KMT2A (0.81) | MEN1KMT2ALMNAGAASMN1; SMN2 | |
| SCHEMBL29516320 | 0.78 | MEN1 (0.86) | MEN1KMT2ALMNAUSP2GAA | |
| SCHEMBL16333074 | 0.78 | KMT2A (0.81) | MEN1KMT2ALMNAGAASMN1; SMN2 | |
| SCHEMBL5072941 | 0.77 | MEN1 (0.78) | MEN1KMT2ALMNAUSP2GAA | |
| SCHEMBL14578666 | 0.77 | L3MBTL1 (0.89) | MEN1KMT2ALMNAUSP2GAA | |
| SCHEMBL6390973 | 0.77 | MEN1 (0.84) | MEN1KMT2ALMNAUSP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287740-A1 | COMPOUNDS AND METHODS FOR TREATING AUTOIMMUNE DISORDERS BY TARGETING HLA-DQ2 | IMMUNOMOLECULAR THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |