SCHEMBL2489326

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2492901	0.90	SCN9A (0.41)	SCN9AMAOAMAOBALDH1A1FPR2
	SCHEMBL15048560	0.89	SCN9A (0.40)	SCN9AMAOAMAOBALDH1A1FPR2
	SCHEMBL2488940	0.89	SCN9A (0.40)	SCN9AMAOAMAOBALDH1A1FPR2
	SCHEMBL2489329	0.88	HDAC8 (0.38)	ALDH1A1L3MBTL1GRM2HDAC11PTGES
	SCHEMBL15060753	0.86	SCN9A (0.42)	SCN9AMAOAMAOBALDH1A1FPR2
	SCHEMBL12209795	0.85	SCN9A (0.44)	SCN9AALDH1A1FPR2PTGES
	SCHEMBL15060822	0.84	SMN1; SMN2 (0.38)	SCN9AMAOAMAOBALDH1A1L3MBTL1
	SCHEMBL13273948	0.84	ALDH1A1 (0.38)	SCN9AMAOAMAOBALDH1A1FPR2
	SCHEMBL15060823	0.83	ALDH1A1 (0.43)	SCN9AMAOAMAOBALDH1A1
	SCHEMBL13274184	0.83	ALDH1A1 (0.36)	SCN9AMAOAMAOBALDH1A1PTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.