Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 11/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CPB1 | P15086 | 4/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14523660 | 0.84 | CPB2 (0.45) | CPB2CYP1A2CPB1SLC7A5ALPI | |
| SCHEMBL7741446 | 0.84 | CPB2 (0.61) | CPB2CYP1A2CPB1 | |
| SCHEMBL8760849 | 0.84 | CPB2 (0.61) | CPB2CYP1A2CPB1 | |
| SCHEMBL365026 | 0.84 | CPB2 (0.45) | CPB2CYP1A2CPB1SLC7A5ALPI | |
| SCHEMBL289025 | 0.82 | ALPI (0.53) | CPB2CYP1A2CPB1SLC7A5ALPI | |
| SCHEMBL41832 | 0.82 | ALPI (0.53) | CPB2CYP1A2CPB1SLC7A5ALPI | |
| SCHEMBL4956555 | 0.82 | ALPI (0.53) | CPB2CYP1A2CPB1SLC7A5ALPI | |
| SCHEMBL6328167 | 0.82 | CPB2 (0.64) | CPB2CYP1A2CPB1 | |
| SCHEMBL10583023 | 0.82 | CPB2 (0.64) | CPB2CYP1A2CPB1 | |
| Hydrochloric Acid SCHEMBL6333571 | 0.81 | CPB2 (0.51) | CPB2CYP1A2CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379513-A1 | HETEROARYL COMPOUNDS USEFUL AS RAF KINASE INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-10-26 | — | — | EP | disclosed |
| EP-2242752-A1 | IMIDAZOLYL BIPHENYL IMIDAZOLES AS HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2010-10-27 | — | — | EP | disclosed |
| WO-2010078408-A1 | HETEROARYL COMPOUNDS USEFUL AS RAF KINASE INHIBITORS | BIOGEN IDEC MA INC. (US) | 2010-07-08 | — | — | WO | disclosed |
| WO-2009102325-A1 | IMIDAZOLYL BIPHENYL IMIDAZOLES AS HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-20 | — | — | WO | disclosed |