SCHEMBL365026

SCHEMBL365026

N[C@@H](Cc1cn(CC(=O)O)cn1)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 13/20 0.45
CPB1 P15086 5/20 0.44
CYP1A2 P05177 1/20 0.42
SLC1A3 P43003 1/20 0.39
ALPI P09923 1/20 0.39
PKM P14618 1/20 0.39
PTGS1 P23219 1/20 0.39
XIAP P98170 1/20 0.39
SLC7A5 Q01650 1/20 0.39
TYR P14679 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14523660 1.00 CPB2 (0.45) CPB2CPB1CYP1A2SLC1A3ALPI
SCHEMBL2489370 0.84 CPB2 (0.46) CPB2CPB1CYP1A2ALPIPKM
SCHEMBL8760849 0.84 CPB2 (0.61) CPB2CPB1CYP1A2
SCHEMBL7741446 0.84 CPB2 (0.61) CPB2CPB1CYP1A2
SCHEMBL14523640 0.84 CPB2 (0.41) CPB2CPB1CYP1A2SLC1A3
SCHEMBL7741830 0.82 CPB2 (0.50) CPB2CPB1CYP1A2
SCHEMBL13634030 0.82 CPB2 (0.42) CPB2CPB1CYP1A2SLC1A3
SCHEMBL22092361 0.82 CPB2 (0.44) CPB2CPB1CYP1A2ALPIPKM
SCHEMBL14344753 0.82 CPB2 (0.42) CPB2CPB1CYP1A2ALPIPKM
SCHEMBL10583023 0.82 CPB2 (0.64) CPB2CPB1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3704 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024141054-A1 PHARMACEUTICAL COMPOSITION COMPRISING FUSION PROTEIN AND USE THEREOF 苏州康宁杰瑞生物科技有限公司 2024-07-04 WO claimed
WO-2024140903-A1 COMPOSITION OF CD40-BINDING MOLECULE AND PHARMACEUTICAL USE THEREOF 苏州盛迪亚生物医药有限公司 2024-07-04 WO claimed
WO-2024120518-A1 IL-17A ANTIBODY FORMULATION AND USE THEREOF 上海华奥泰生物药业股份有限公司 2024-06-13 WO claimed
WO-2024088293-A1 COMPOSITION COMPRISING ANTI-MASP2 ANTIBODY, AND PHARMACEUTICAL USE 江苏恒瑞医药股份有限公司 2024-05-02 WO claimed
CN-117942300-A Liquid formulations comprising anti-IL-17 antibodies 甘李药业股份有限公司 2024-04-30 CN claimed
CN-111375059-B anti-GITR antibody pharmaceutical composition and application thereof 江苏恒瑞医药股份有限公司 2024-04-16 CN claimed
CN-112543647-B TIM3 antibody pharmaceutical composition and application thereof 江苏恒瑞医药股份有限公司 2024-04-16 CN claimed
CN-113713094-B anti-IL-6R antibody pharmaceutical composition and application thereof 江苏恒瑞医药股份有限公司 2024-03-15 CN claimed
US-20240024498-A1 PHARMACEUTICAL COMPOSITION COMPRISING ANTIBODY-DRUG CONJUGATE, AND USE OF PHARMACEUTICAL COMPOSITION SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. (CN) 2024-01-25 US claimed
US-20240016931-A1 ANTI-TSLP ANTIBODY PHARMACEUTICAL COMPOSITION AND USE THEREOF SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. (CN) 2024-01-18 US claimed
CN-102281901-A Therapeutic protein formulations 2011-12-14 CN claimed
EP-2371388-A2 Antibody formulations Genentech, Inc. (US) 2011-10-05 EP claimed
EP-2358393-A1 THERAPEUTIC PROTEIN FORMULATIONS F.HOFFMANN-LA ROCHE AG (CH) 2011-08-24 EP claimed
CN-101084015-B Antibody formulations in histidine-acetate buffer GENENTECH INC 2011-08-10 CN claimed
WO-2010059787-A1 THERAPEUTIC PROTEIN FORMULATIONS GENENTECH, INC. (US) 2010-05-27 WO claimed
US-20100015157-A1 ANTIBODY FORMULATIONS GENENTECH, INC. (US) 2010-01-21 US claimed
CN-101084015-A Antibody formulations in histidine-acetate buffer GENENTECH INC (US) 2007-12-05 CN claimed
EP-1802344-A2 ANTIBODY FORMULATION IN HISTIDINE-ACETATE BUFFER Genentech, Inc. (US) 2007-07-04 EP claimed
WO-2006044908-A2 ANTIBODY FORMULATION IN HISTIDINE-ACETATE BUFFER GENENTECH, INC. (US) 2006-04-27 WO claimed
US-20060088523-A1 Antibody formulations GENENTECH, INC. 2006-04-27 US claimed