SCHEMBL24894145

SCHEMBL24894145

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nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.33
THRB P10828 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24894079 0.81 ALDH1A1 (0.30) LMNA
SCHEMBL29796427 0.77 TDP1 (0.34) TDP1THRBLMNA
SCHEMBL21342069 0.77 TDP1 (0.34) TDP1THRBLMNA
SCHEMBL30476153 0.77 TDP1 (0.34) TDP1THRBLMNA
SCHEMBL20306974 0.77 SPHK2 (0.34) THRBLMNA
SCHEMBL29202212 0.77 TDP1 (0.34) TDP1THRBLMNA
SCHEMBL11079165 0.77 SPHK2 (0.34) THRBLMNA
SCHEMBL5197132 0.76 SPHK2 (0.30)
SCHEMBL12489792 0.76 SLC1A1 (0.44)
SCHEMBL1660373 0.75 THRB (0.32) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023288015-A1 M6PR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. (US) 2023-01-19 WO disclosed