SCHEMBL24894584

SCHEMBL24894584

CNc1cc(OC)c(N)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY4 P51582 11/20 0.54
P2RY2 P41231 6/20 0.54
MAPT P10636 4/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
ALDH1A1 P00352 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
KDM4E B2RXH2 1/20 0.51
USP2 O75604 1/20 0.51
DUSP3 P51452 1/20 0.51
RAB9A P51151 4/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
MAPK1 P28482 2/20 0.51
ADORA2A P29274 2/20 0.51
FGB P02675 1/20 0.51
POLB P06746 1/20 0.51
THRB P10828 1/20 0.51
PPARG P37231 1/20 0.51
NCOA2 Q15596 1/20 0.51
NCOA1 Q15788 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12552943 0.85 P2RY4 (0.61) P2RY4P2RY2METGNG2GNB1
SCHEMBL14391016 0.85 P2RY4 (0.51) P2RY4P2RY2MAPTMEN1KMT2A
SCHEMBL12593712 0.84 MAPT (0.53) P2RY4P2RY2MAPTMEN1KMT2A
SCHEMBL7566865 0.82 CDK2 (0.56) P2RY4P2RY2MAPTMEN1KMT2A
SCHEMBL460432 0.81 MAPT (0.66) P2RY4P2RY2MAPTMEN1KMT2A
SCHEMBL12593746 0.81 P2RY4 (0.65) P2RY4P2RY2MAPTALDH1A1KDM4E
SCHEMBL12593748 0.80 MEN1 (0.66) P2RY4P2RY2MAPTMEN1KMT2A
SCHEMBL10812624 0.80 GNG2 (0.64) P2RY4P2RY2METGNG2GNB1
SCHEMBL11489194 0.80 MEN1 (0.63) P2RY4P2RY2MAPTMEN1KMT2A
SCHEMBL92468 0.80 CYP1A1 (0.62) P2RY4P2RY2MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023286282-A1 FIRE RETARDANT AND SIMULTANEOUSLY DYEING METHOD FOR POLYESTER-BASED TEXTILE 大京化学株式会社 2023-01-19 WO disclosed