SCHEMBL460432

SCHEMBL460432

COc1cc(N)c2c(c1N)C(=O)c1ccccc1C2=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.66
MEN1 O00255 6/20 0.66
KMT2A Q03164 6/20 0.66
ADORA2A P29274 5/20 0.66
ALDH1A1 P00352 4/20 0.66
RAB9A P51151 4/20 0.66
SMN1; SMN2 Q16637 4/20 0.66
POLB P06746 4/20 0.66
THRB P10828 2/20 0.66
MAPK1 P28482 2/20 0.66
NPSR1 Q6W5P4 2/20 0.66
FGB P02675 1/20 0.66
PPARG P37231 1/20 0.66
NCOA2 Q15596 1/20 0.66
NCOA1 Q15788 1/20 0.66
KDM4E B2RXH2 3/20 0.58
TDP1 Q9NUW8 3/20 0.58
USP2 O75604 2/20 0.58
DUSP3 P51452 1/20 0.58
MCL1 Q07820 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11179290 0.84 FTO (0.55) MAPTMEN1KMT2AADORA2AALDH1A1
SCHEMBL2207839 0.84 KMT2A (0.54) MAPTMEN1KMT2AADORA2AALDH1A1
SCHEMBL11023123 0.83 MEN1 (0.55) MAPTMEN1KMT2AADORA2AALDH1A1
SCHEMBL8748152 0.83 MAPT (0.50) MAPTMEN1KMT2AADORA2AALDH1A1
SCHEMBL10815326 0.82 ADORA2A (0.49) MAPTMEN1KMT2AADORA2AALDH1A1
SCHEMBL24894584 0.81 P2RY4 (0.54) MAPTMEN1KMT2AADORA2AALDH1A1
SCHEMBL92415 0.81 ADORA2A (0.66) MAPTMEN1KMT2AADORA2AALDH1A1
SCHEMBL13352362 0.80 MEN1 (0.54) MAPTMEN1KMT2AADORA2AALDH1A1
SCHEMBL11345777 0.80 MEN1 (0.61) MAPTMEN1KMT2AADORA2AALDH1A1
SCHEMBL2303569 0.79 MAPT (1.00) MAPTMEN1KMT2AADORA2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 443 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116837490-B Polymer coloring method, spinning color paste, spinning solution and colored fiber 江苏新视界先进功能纤维创新中心有限公司 2025-04-15 CN claimed
CN-116837484-B Polymer coloring method, spinning solution and colored fiber 江苏新视界先进功能纤维创新中心有限公司 2024-12-10 CN claimed
CN-116988184-B Polymer coloring method, spinning color paste, spinning solution and colored fiber 江苏新视界先进功能纤维创新中心有限公司 2024-10-01 CN claimed
CN-116837483-B Polymer coloring method, spinning solution and colored fiber 江苏新视界先进功能纤维创新中心有限公司 2024-10-01 CN claimed
CN-117820586-A Cationic waterborne polyurethane type macromolecular dye and preparation method thereof 香港理工大学深圳研究院 2024-04-05 CN claimed
CN-116988184-A Polymer coloring method, spinning color paste, spinning solution and colored fiber 江苏新视界先进功能纤维创新中心有限公司 2023-11-03 CN claimed
CN-116837484-A Polymer coloring method, spinning solution and colored fiber 江苏新视界先进功能纤维创新中心有限公司 2023-10-03 CN claimed
CN-116837490-A Polymer coloring method, spinning color paste, spinning solution and colored fiber 江苏新视界先进功能纤维创新中心有限公司 2023-10-03 CN claimed
CN-116837483-A Polymer coloring method, spinning solution and colored fiber 江苏新视界先进功能纤维创新中心有限公司 2023-10-03 CN claimed
WO-2003099242-A1 COSMETIC AGENTS CONTAINING PROTEIN DISULFIDE ISOMERASE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-12-04 WO claimed
EP-0843993-B1 Composition and process for dyeing hair WELLA AG (DE) 2003-08-06 EP claimed
EP-0843994-B1 Composition and process for dyeing hair WELLA AG (DE) 2003-08-06 EP claimed
EP-0463993-B1 Process for the preparation of aminoanthraquinone derivatives CIBA SC HOLDING AG (CH) 2002-05-02 EP claimed
US-5965114-A DYE CONTAINING MASS OF COSMETIC CARRIER AND 5-BROMO-4-CHLORO-3-INDOLYL-B-D-GALACTOSIDE; READY-TO-USE DYE IS OBTAINED BY MIXING THE DYE CONTAINING MASS WITH A HYDROLASE ENZYME; EASILY CONVERTED INDIGO DYE PRECURSOR WELLA AG (DE) 1999-10-12 US claimed
EP-0843993-A2 Composition and process for dyeing hair Wella Aktiengesellschaft (DE) 1998-05-27 EP claimed
EP-0843994-A2 Composition and process for dyeing hair Wella Aktiengesellschaft (DE) 1998-05-27 EP claimed
US-5196553-A From bromaminic acid and a benzenesulfonamide or an amide, copper/I/ catalyst formed by in situ reduction of a copper/II/ salt, less copper required CIBA-GEIGY CORPORATION (US) 1993-03-23 US claimed
EP-0460127-B1 HAIR TONING AGENT IN FOAM FORM Wella Aktiengesellschaft (DE) 1993-01-20 EP claimed
EP-0463993-A1 Process for the preparation of aminoanthraquinone derivatives CIBA-GEIGY AG (CH) 1992-01-02 EP claimed
US-H231-H Rocket fuel THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1987-03-03 US claimed