SCHEMBL2489540

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12160563	0.93	NPSR1 (0.43)	RAB9ACLK1CHRM1MAPTNPSR1
	SCHEMBL2489936	0.91	PIN1 (0.37)	RAB9ACLK1MAPTNPSR1L3MBTL1
	SCHEMBL2581807	0.90	CHRM1 (0.45)	RAB9ACLK1CHRM1PDE4DGFER
	SCHEMBL2466272	0.90	TNF (0.44)	RAB9ACLK1CHRM1
	Hydrochloric Acid SCHEMBL13560349	0.88	CHRM1 (0.41)	RAB9ACLK1CHRM1EGFRPDE4B
	SCHEMBL15472265	0.88	CHRM1 (0.43)	RAB9ACLK1CHRM1NPC1MAPT
	SCHEMBL1136185	0.86	CHRM1 (0.41)	RAB9ACLK1CHRM1NPC1KDM4E
	SCHEMBL7914523	0.86	CHRM1 (0.39)	RAB9ACLK1CHRM1MAPTKDM4E
	SCHEMBL17970287	0.86	CHRM1 (0.41)	RAB9ACLK1CHRM1NPC1KDM4E
	SCHEMBL2466832	0.85	CHRM1 (0.39)	RAB9ACLK1CHRM1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.