SCHEMBL2489555

SCHEMBL2489555

NC(=O)C=CN1CCCC1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
LMNA P02545 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA3 P07451 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA13 Q8N1Q1 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
BLM P54132 1/20 0.36
KMT2A Q03164 4/20 0.35
BRD4 O60885 1/20 0.34
BRD2 P25440 1/20 0.34
ALDH1A1 P00352 2/20 0.33
PIK3CD O00329 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23106943 0.84 BLM (0.41) TSHRLMNACA12CA1CA2
Hydrogen Peroxide SCHEMBL15262924 0.82 BLM (0.47) TSHRLMNABLMKMT2ABRD4
SCHEMBL7064387 0.82 BLM (0.47) TSHRLMNABLMKMT2ABRD4
SCHEMBL14314391 0.82 BLM (0.47) TSHRLMNABLMKMT2ABRD4
SCHEMBL5815717 0.77 NFE2L2 (0.42) TSHRLMNABLMKMT2ABRD4
Acrylamide SCHEMBL1162173 0.76 TSHR (0.42) TSHRLMNACA12CA1CA2
Acrylamide SCHEMBL18066844 0.76 TSHR (0.42) TSHRLMNACA12CA1CA2
SCHEMBL7646912 0.75
SCHEMBL7109892 0.75
SCHEMBL1177989 0.74 TSHR (0.34) TSHRLMNABLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109796954-B Temperature-resistant salt-resistant water-soluble multi-component copolymer and preparation method and application thereof 中国石油化工股份有限公司 2021-07-06 CN disclosed
CN-109796954-A A kind of temperature-resistant anti-salt water solubility multiple copolymer and the preparation method and application thereof 中国石油化工股份有限公司 2019-05-24 CN disclosed
EP-2838577-A1 HYDROPHILIC POLYMERIC COATINGS FOR MEDICAL ARTICLES WITH VISUALIZATION MOIETY SurModics, Inc. (US) 2015-02-25 EP disclosed
US-8956682-B2 Hydrophilic polymeric coatings for medical articles with visualization moiety SURMODICS, INC. (US) 2015-02-17 US disclosed
WO-2013151991-A1 HYDROPHILIC POLYMERIC COATINGS FOR MEDICAL ARTICLES WITH VISUALIZATION MOIETY SURMODICS, INC. (US) 2013-10-10 WO disclosed
US-20130261566-A1 HYDROPHILIC POLYMERIC COATINGS FOR MEDICAL ARTICLES WITH VISUALIZATION MOIETY SURMODICS, INC. (US) 2013-10-03 US disclosed
CN-102786918-A Water loss reducing composition, cement composition containing water loss reducing composition, and preparation method and use of water loss reducing composition CHINA CBM CO LTD 2012-11-21 CN disclosed
US-20110256087-A1 COSMETIC COMPOSITION CONTAINING A LOCUST BEAN GUM HYDROLYSATE PIERRE FABRE DERMO-COSMETIQUE (FR) 2011-10-20 US disclosed
EP-2376055-A1 COSMETIC COMPOSITION CONTAINING A LOCUST BEAN GUM HYDROLYSATE Pierre Fabre Dermo-Cosmétique (FR) 2011-10-19 EP disclosed
CN-100594217-C Ampholytic copolymer and use thereof BASF AG 2010-03-17 CN disclosed
CN-1756780-A Ampholytic copolymer and use thereof BASF AG (DE) 2006-04-05 CN disclosed
US-5104933-A Preparation of copolymers of polyvinyl alcohols MOBIL OIL CORP. (US) 1992-04-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110256087-A1 COSMETIC COMPOSITION CONTAINING A LOCUST BEAN GUM HYDROLYSATE TYR, LCT, GGH TSHR 3792/4885LMNA 2084/4885CA12 581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.