SCHEMBL24896278

SCHEMBL24896278

Cn1c(C(=O)NC23CCC(C2)C3)cc2ccnc(Cl)c21

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 16/20 0.40
▸ CNR1 P21554 2/20 0.37
▸ SLC6A9 P48067 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24896434 0.88 CNR2 (0.41) CNR2CNR1SLC6A9
SCHEMBL24896277 0.83 ANO1 (0.40) CNR2CNR1
SCHEMBL24896350 0.81 GRM4 (0.41) CNR2CNR1
SCHEMBL24896285 0.80 ANO1 (0.40) CNR2
SCHEMBL24896287 0.78 PDE4B (0.38) CNR2
SCHEMBL24896281 0.78 PDE4B (0.50) CNR1
SCHEMBL25002467 0.77 PDE4B (0.39) CNR2CNR1
SCHEMBL24896283 0.76 GRM4 (0.39) —
SCHEMBL24896288 0.76 KDM4E (0.50) CNR2CNR1
SCHEMBL24896282 0.73 TP53 (0.41) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370207-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS Nido Biosciences, Inc. (US) 2024-05-22 — — EP disclosed
US-20230039586-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. 2023-02-09 — — US disclosed
WO-2023287704-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. (US) 2023-01-19 — — WO disclosed
WO-2023287704-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. (US) 2023-01-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230039586-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 CNR2 997/4885CNR1 633/4885SLC6A9 4520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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