Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 4/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24897864 | 0.81 | DGAT1 (0.36) | DGAT1ALOX5APFEN1CNR2 | |
| SCHEMBL2420158 | 0.78 | CNR2 (0.47) | DGAT1ALOX5APFEN1NPC1CNR2 | |
| SCHEMBL31748586 | 0.78 | DGAT1 (0.35) | DGAT1NPC1 | |
| SCHEMBL8218766 | 0.77 | DGAT1 (0.36) | DGAT1ALOX5APFEN1NPC1CNR2 | |
| SCHEMBL3061829 | 0.77 | DGAT1 (0.36) | DGAT1ALOX5APFEN1NPC1CNR2 | |
| SCHEMBL24897874 | 0.72 | ALDH1A1 (0.33) | DGAT1 | |
| SCHEMBL31425313 | 0.71 | DGAT1 (0.37) | DGAT1NPC1 | |
| SCHEMBL31748734 | 0.71 | DGAT1 (0.35) | DGAT1NPC1 | |
| SCHEMBL15721885 | 0.71 | DGAT1 (0.37) | DGAT1NPC1 | |
| SCHEMBL15808369 | 0.71 | NPC1 (0.32) | DGAT1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288242-A1 | PI3Kα INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023288242-A1 | PI3Kα INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |