Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13828216 | 0.73 | OPRM1 (0.55) | KCNN4CYP2C19CYP1A2OPRM1DRD3 | |
| SCHEMBL7789748 | 0.73 | KCNN4 (0.42) | KCNN4CYP2C19ESR1ESR2CYP1A2 | |
| Triphenylmethanethiol SCHEMBL5674467 | 0.70 | CYP2C19 (0.44) | KCNN4CYP2C19ESR1ESR2CYP1A2 | |
| SCHEMBL4307361 | 0.69 | CYP2C19 (0.56) | KCNN4CYP2C19ESR1ESR2CYP1A2 | |
| SCHEMBL3889406 | 0.69 | KCNN4 (0.52) | KCNN4CYP2C19ESR1ESR2CYP1A2 | |
| SCHEMBL17153845 | 0.69 | KCNN4 (0.41) | KCNN4CYP2C19ESR1ESR2CYP1A2 | |
| SCHEMBL14910050 | 0.67 | KCNN4 (0.50) | KCNN4CYP2C19ESR1ESR2CYP1A2 | |
| Triphenylmethanethiol SCHEMBL5674474 | 0.67 | KCNN4 (0.39) | KCNN4CYP2C19ESR1ESR2CYP1A2 | |
| SCHEMBL767319 | 0.65 | KCNN4 (0.46) | KCNN4CYP2C19ESR1ESR2CYP1A2 | |
| Propane SCHEMBL27957403 | 0.65 | CYP2C19 (0.46) | KCNN4CYP2C19ESR1ESR2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130273609-A1 | PRIMER BEADS | Chemistry and Technology For Genes, Inc. (US) | 2013-10-17 | — | — | US | disclosed |
| WO-2012003388-A1 | PRIMER BEADS | CHEMISTRY AND TECHNOLOGY FOR GENES (US) | 2012-01-05 | — | — | WO | disclosed |