SCHEMBL2489928

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2492107	0.98	HTR1A (0.42)	HTR1AHTR7ALDH1A1MAPK1CYP1A2
	SCHEMBL2493820	0.96	BCHE (0.40)	HTR1AHTR7ALDH1A1MAPK1CYP1A2
	SCHEMBL2492036	0.92	HTR1A (0.37)	HTR1AHTR7ALDH1A1MAPK1CYP1A2
	SCHEMBL2492005	0.92	HRH3 (0.43)	HTR1AHTR7KCNH2HRH3BCHE
	SCHEMBL2494722	0.92	HTR1A (0.44)	HTR1AHTR7ALDH1A1MAPK1CHRM1
	SCHEMBL2493992	0.92	HTR1A (0.44)	HTR1AHTR7ALDH1A1CHRM1HRH3
	SCHEMBL12160513	0.91	HTR1A (0.43)	HTR1AHTR7CHRM1KCNH2HRH3
	Hydrochloric Acid SCHEMBL2493996	0.90	HTR1A (0.42)	HTR1AHTR7CHRM1KCNH2HRH3
	SCHEMBL2496305	0.90	HTR1A (0.46)	HTR1AHTR7ALDH1A1CHRM1HRH3
	SCHEMBL2460946	0.88	POLB (0.43)	ALDH1A1KDM4EGAAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.