Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.56 |
| ▸ | MME | P08473 | 7/20 | 0.52 |
| ▸ | ACE | P12821 | 6/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.52 |
| ▸ | CPA1 | P15085 | 5/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | FCER2 | P06734 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9978223 | 0.92 | PSMB5 (0.56) | HPGDSACEPSMB5MMP1FCER2 | |
| SCHEMBL24183726 | 0.92 | PSMB5 (0.56) | HPGDSACEPSMB5MMP1FCER2 | |
| SCHEMBL7903892 | 0.88 | MME (0.66) | MMEACEACE2CPA1 | |
| SCHEMBL7901632 | 0.88 | MME (0.66) | MMEACEACE2CPA1 | |
| SCHEMBL22338710 | 0.85 | GRIA1 (0.45) | HPGDSACEPSMB5MMP1FCER2 | |
| SCHEMBL26909780 | 0.84 | HPGDS (0.58) | HPGDSMMEACEACE2CPA1 | |
| SCHEMBL4348297 | 0.84 | HPGDS (0.58) | HPGDSMMEACEACE2CPA1 | |
| SCHEMBL27761115 | 0.84 | HDAC1 (0.69) | HDAC1HDAC6 | |
| SCHEMBL16823433 | 0.82 | HPGDS (0.53) | HPGDSMMEACEACE2CPA1 | |
| SCHEMBL27258868 | 0.82 | ACACB (0.62) | MMEACEACE2CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288213-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-19 | — | — | WO | disclosed |