Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 5/20 | 0.47 |
| ▸ | MDM4 | O15151 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29221366 | 0.92 | MDM4 (0.52) | MDM2MDM4TP53SLC17A5CASP3 | |
| SCHEMBL29221368 | 0.92 | MDM4 (0.52) | MDM2MDM4TP53SLC17A5CASP3 | |
| SCHEMBL24915228 | 0.84 | MDM4 (0.43) | MDM2MDM4TP53SLC17A5CASP3 | |
| SCHEMBL29547912 | 0.83 | MDM4 (0.53) | MDM2MDM4TP53SLC17A5CASP3 | |
| SCHEMBL29397967 | 0.83 | MDM4 (0.53) | MDM2MDM4TP53SLC17A5CASP3 | |
| SCHEMBL3725027 | 0.83 | MDM4 (0.53) | MDM2MDM4TP53SLC17A5CASP3 | |
| SCHEMBL800112 | 0.83 | MDM4 (0.53) | MDM2MDM4TP53SLC17A5CASP3 | |
| SCHEMBL29401862 | 0.83 | MDM4 (0.53) | MDM2MDM4TP53SLC17A5CASP3 | |
| SCHEMBL3725031 | 0.83 | MDM4 (0.53) | MDM2MDM4TP53SLC17A5CASP3 | |
| SCHEMBL24899402 | 0.82 | MDM4 (0.46) | MDM2MDM4TP53SLC17A5CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192873-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023288213-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-19 | — | — | WO | disclosed |