Sugi Predict

Sugi Predict / Compounds / SCHEMBL29401862

SCHEMBL29401862

SCHEMBL29401862

O=C(N[C@@H](Cc1cccc2ccccc12)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.53
▸ TP53 P04637 3/20 0.53
▸ SLC17A5 Q9NRA2 1/20 0.49
▸ CASP3 P42574 2/20 0.48
▸ HRH4 Q9H3N8 1/20 0.48
▸ TGM2 P21980 1/20 0.48
▸ MME P08473 1/20 0.47
▸ ACE P12821 1/20 0.47
▸ CPA1 P15085 1/20 0.47
▸ ACE2 Q9BYF1 1/20 0.47
▸ MDM2 Q00987 4/20 0.47
▸ CTSS P25774 1/20 0.46
▸ CTSK P43235 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29547912 1.00 MDM4 (0.53) MDM4TP53SLC17A5CASP3HRH4
SCHEMBL800112 1.00 MDM4 (0.53) MDM4TP53SLC17A5CASP3HRH4
SCHEMBL29397967 1.00 MDM4 (0.53) MDM4TP53SLC17A5CASP3HRH4
SCHEMBL3725027 1.00 MDM4 (0.53) MDM4TP53SLC17A5CASP3HRH4
SCHEMBL3725031 1.00 MDM4 (0.53) MDM4TP53SLC17A5CASP3HRH4
SCHEMBL13978398 0.91 MDM4 (0.47) MDM4TP53SLC17A5CASP3CTSS
SCHEMBL24915806 0.89 MDM4 (0.50) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL30229636 0.89 MDM4 (0.50) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL29221380 0.89 MDM4 (0.50) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL30229510 0.89 MDM4 (0.50) MDM4TP53SLC17A5CASP3MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12616761-B2 CXCR4-targeting compounds THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2026-05-05 — — US disclosed
WO-2026086847-A1 CYCLOPEPTIDE DRUG CONJUGATE AND USE THEREOF 中山医诺维申新药研发有限公司 2026-04-30 — — WO disclosed
US-12539335-B2 Tricyclic polypeptide conjugated drug and use thereof CONJUSTAR (ZHUHAI) BIOLOGICS CO., LTD. (CN) 2026-02-03 — — US disclosed
US-20260022142-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL MYERS SQUIBB CO (US) 2026-01-22 — — US disclosed
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY (US) 2026-01-01 — — US disclosed
EP-4653451-A1 POLYPEPTIDE COMPOUND AND USE THEREOF Chengdu New Radiomedicine Technology Co., Ltd. (CN) 2025-11-26 — — EP disclosed
EP-3746467-B1 MODIFIED LIPIDATED RELAXIN B CHAIN PEPTIDES AND THEIR THERAPEUTIC USE SANOFI SA (FR) 2025-10-08 — — EP disclosed
US-20250250299-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY 2025-08-07 — — US disclosed
US-12371461-B2 Nemo coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2025-07-29 — — US disclosed
EP-3303367-B1 STABILIZED MINIMAL COILED-COIL MIMETICS UNIV NEW YORK (US) 2025-06-18 — — EP disclosed
WO-2023028008-A2 COMBINATION OF RELAXIN AND VASOPRESSIN ANALOGUES FOR TREATMENT OF RENAL DISORDERS OR CONDITIONS RIVER 2 RENAL CORP. (US) 2023-03-02 — — WO disclosed
US-20220411468-A1 PEPTIDE MACROCYCLES AGAINST ACINETOBACTER BAUMANNII HOFFMANN-LA ROCHE INC. (US) 2022-12-29 — — US disclosed
US-20220289802-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME CORNELL UNIVERSITY 2022-09-15 — — US disclosed
US-11440938-B2 Stabilized minimal coiled-coil mimetics NEW YORK UNIVERSITY (US) 2022-09-13 — — US disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
CN-109476704-B Antibacterial cyclic lipopeptides 港大科桥有限公司 2022-08-16 — — CN disclosed
CN-109134610-B Peptide compound, application thereof and composition containing peptide compound 尚华医药科技(江西)有限公司 2022-07-08 — — CN disclosed
WO-2022082312-A1 NOVEL CXCR4-TARGETING COMPOUNDS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2022-04-28 — — WO disclosed
WO-2022084486-A1 SELF-PURIFIED NUCLEIC ACID ENCODED LIBRARIES ETH ZURICH (CH) 2022-04-28 — — WO disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220411468-A1 PEPTIDE MACROCYCLES AGAINST ACINETOBACTER BAUMANNII VIP, ARG1, CX3CR1 MDM4 3771/4885TP53 3724/4885SLC17A5 2862/4885
US-12371461-B2 Nemo coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH MDM4 2743/4885TP53 3446/4885SLC17A5 3328/4885
US-11440938-B2 Stabilized minimal coiled-coil mimetics COIL, CALCOCO2, SMC2 MDM4 256/4885TP53 657/4885SLC17A5 3975/4885
US-20260022142-A1 MACROCYCLIC IMMUNOMODULATORS CD274, PDCD1LG2, PDCD1 MDM4 3040/4885TP53 421/4885SLC17A5 3929/4885
US-12616761-B2 CXCR4-targeting compounds CXCR4, CXCR2, CXCR3 MDM4 3817/4885TP53 1733/4885SLC17A5 1202/4885
US-20250250299-A1 MACROCYCLIC IMMUNOMODULATORS CD274, PDCD1LG2, PDCD1 MDM4 1128/4885TP53 158/4885SLC17A5 3674/4885
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME DDX21, PHAX, RBX1 MDM4 2407/4885TP53 2772/4885SLC17A5 4312/4885
US-20220289802-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME COIL, CALCOCO2, NCAPH MDM4 2743/4885TP53 3446/4885SLC17A5 3328/4885
US-12539335-B2 Tricyclic polypeptide conjugated drug and use thereof NECTIN4, SELPLG, ITGB4 MDM4 2657/4885TP53 1060/4885SLC17A5 87/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.