Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21821980 | 0.91 | MAPT (0.65) | MAP1LC3BALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL22057834 | 0.90 | ALDH1A1 (0.68) | MAP1LC3BALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL22056812 | 0.85 | MAP1LC3B (0.65) | MAP1LC3BALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL22056802 | 0.83 | MAP1LC3B (0.65) | MAP1LC3BALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL21821782 | 0.82 | MEN1 (0.49) | MAP1LC3BALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL21821986 | 0.82 | MEN1 (0.66) | MAP1LC3BALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL22056820 | 0.82 | MAP1LC3B (0.60) | MAP1LC3BALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL21773997 | 0.81 | ALDH1A1 (0.47) | MAP1LC3BALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL22057719 | 0.81 | HTT (0.65) | MAP1LC3BMAPTLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL22056816 | 0.80 | ALDH1A1 (0.55) | MAP1LC3BALDH1A1MAPTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284420-A1 | APPLICATION OF POLYCYCLIC ARYL COMPOUND IN PREPARATION OF ANTIFUNGAL DRUG | 暨南大学附属第一医院 | 2023-01-19 | — | — | WO | disclosed |