Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | TPMT | P51580 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24782522 | 0.77 | HPGD (0.50) | — | |
| SCHEMBL24899679 | 0.77 | CYP2A6 (0.36) | — | |
| SCHEMBL14966174 | 0.76 | CA2 (0.44) | — | |
| SCHEMBL24899727 | 0.74 | — | — | |
| SCHEMBL18486590 | 0.68 | HPGD (0.45) | EPHX1 | |
| SCHEMBL8148549 | 0.68 | SMYD3 (0.39) | — | |
| SCHEMBL14966208 | 0.68 | GAA (0.44) | — | |
| SCHEMBL14966930 | 0.68 | GAA (0.44) | — | |
| SCHEMBL24899757 | 0.67 | HPGD (0.42) | TPMT | |
| SCHEMBL24782533 | 0.67 | HDAC1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024010963-A1 | HETEROARYL COMPOUNDS AS INHIBITORS OF TYK2/JAK1, COMPOSITION AND APPLICATION THEREOF | ACCRO BIOSCIENCE (HK) LIMITED (CN) | 2024-01-11 | — | — | WO | disclosed |
| WO-2023284869-A1 | SULFUR/PHOSPHORUS-CONTAINING ARYL COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2023-01-19 | — | — | WO | disclosed |