Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966208 | 0.95 | GAA (0.44) | GAASMN1; SMN2CA2CA4CA5A | |
| SCHEMBL778386 | 0.93 | SMN1; SMN2 (0.43) | GAASMN1; SMN2CA2CA4CA5A | |
| SCHEMBL14966174 | 0.91 | CA2 (0.44) | GAASMN1; SMN2CA2CA4CA5A | |
| SCHEMBL8148549 | 0.81 | SMYD3 (0.39) | GAASMN1; SMN2CA2CA4CA5A | |
| SCHEMBL24250384 | 0.78 | GAA (0.33) | GAASMN1; SMN2CYP3A4CYP2C19HTT | |
| SCHEMBL13321940 | 0.77 | GAA (0.53) | GAASMN1; SMN2CA2CA4CA5A | |
| SCHEMBL8023632 | 0.77 | GAA (0.34) | GAASMN1; SMN2CA2CA4CA5A | |
| SCHEMBL778610 | 0.76 | SMN1; SMN2 (0.52) | GAASMN1; SMN2CA2CA4CA5A | |
| SCHEMBL8597062 | 0.75 | ALDH1A1 (0.39) | GAASMN1; SMN2CA2CA4CA5A | |
| SCHEMBL778811 | 0.74 | SMN1; SMN2 (0.42) | GAASMN1; SMN2CA2CA4CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9505859-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2016-11-29 | — | — | US | disclosed |
| EP-2780381-B1 | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORP (JP) | 2015-10-07 | — | — | EP | disclosed |
| US-20140303327-A1 | Process For Producing Polydienes | BRIDGESTONE CORPORATION (JP) | 2014-10-09 | — | — | US | disclosed |
| EP-2780381-A1 | PROCESS FOR PRODUCING POLYDIENES | Bridgestone Corporation (JP) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013075085-A1 | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORPORATION (JP) | 2013-05-23 | — | — | WO | disclosed |