Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 10/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16451486 | 0.84 | KDM4E (0.38) | KDM4EKMT2AHTTCRHR1 | |
| SCHEMBL5018836 | 0.76 | NFKB1 (0.38) | — | |
| SCHEMBL1425326 | 0.76 | KMT2A (0.59) | KDM4EKMT2AHTTCRHR1POLB | |
| SCHEMBL1603021 | 0.73 | KMT2A (0.67) | KDM4EKMT2AHTTCRHR1POLB | |
| SCHEMBL20642343 | 0.72 | ESR1 (0.35) | KDM4EKMT2ACRHR1 | |
| SCHEMBL2790492 | 0.72 | KDM4E (0.65) | KDM4EKMT2AHTTCRHR1POLB | |
| SCHEMBL12484062 | 0.71 | KMT2A (0.46) | KDM4EKMT2AHTTCRHR1PGK1 | |
| SCHEMBL9073351 | 0.70 | KMT2A (1.00) | KDM4EKMT2AHTTCRHR1POLB | |
| SCHEMBL2562194 | 0.70 | KDM4E (0.53) | KDM4EKMT2AHTTCRHR1 | |
| SCHEMBL16019521 | 0.69 | CRHR1 (0.41) | KDM4EKMT2ACRHR1CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283921-A1 | DPD INHIBITOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 北京深蓝泰医药科技有限公司 | 2023-01-19 | — | — | WO | disclosed |