Tretoquinol

Tretoquinol

SCHEMBL249002

COc1cc(CC2NCCc3cc(O)c(O)cc32)cc(OC)c1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TBXA2R P21731 6/20 1.00
ADRB2 P07550 5/20 1.00
ADRB1 P08588 4/20 1.00
ADRB3 P13945 3/20 1.00
HTR1A P08908 1/20 1.00
ADRA2A P08913 1/20 1.00
DRD1 P21728 1/20 1.00
PTGS1 P23219 1/20 1.00
OPRM1 P35372 1/20 1.00
DRD3 P35462 1/20 1.00
DHFR P00374 1/20 1.00
KDM4E B2RXH2 1/20 0.67
MAPT P10636 1/20 0.67
PKM P14618 1/20 0.67
MEN1 O00255 1/20 0.66
ABL1 P00519 1/20 0.66
ALPL P05186 1/20 0.66
GAA P10253 1/20 0.66
KMT2A Q03164 1/20 0.66
RIN1 Q13671 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tretoquinol SCHEMBL29383882 1.00 TBXA2R (1.00) TBXA2RADRB2ADRB1ADRB3HTR1A
Tretoquinol SCHEMBL249003 1.00 TBXA2R (1.00) TBXA2RADRB2ADRB1ADRB3HTR1A
Tretoquinol SCHEMBL9053034 0.99 TBXA2R (0.97) TBXA2RADRB2ADRB1ADRB3HTR1A
Tretoquinol SCHEMBL30537714 0.99 TBXA2R (0.97) TBXA2RADRB2ADRB1ADRB3HTR1A
Tretoquinol SCHEMBL1604695 0.99 TBXA2R (0.97) TBXA2RADRB2ADRB1ADRB3HTR1A
Tretoquinol SCHEMBL1630263 0.99 TBXA2R (0.97) TBXA2RADRB2ADRB1ADRB3HTR1A
Tretoquinol SCHEMBL29966739 0.99 TBXA2R (0.97) TBXA2RADRB2ADRB1ADRB3HTR1A
Tretoquinol SCHEMBL11040376 0.97 TBXA2R (0.95) TBXA2RADRB2ADRB1ADRB3HTR1A
SCHEMBL12635396 0.89 ADRB2 (0.80) TBXA2RADRB2ADRB1ADRB3HTR1A
SCHEMBL17713983 0.89 ADRB2 (0.80) TBXA2RADRB2ADRB1ADRB3HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2329 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722714-A1 SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) Korea Institute of Science and Technology (KR) 2026-04-08 EP claimed
US-20250213647-A1 CHEMOKINE RECEPTORS AND ALPHA1 ADRENERGIC RECEPTORS/VASOPRESSIN RECEPTORS 1A HETEROMERS AS DRUG TARGETS FOR DISEASE UNIVERSITY OF SOUTH FLORIDA 2025-07-03 US claimed
CN-119233997-A Tetrahedral antibodies 生物分子控股有限责任公司 2024-12-31 CN claimed
US-20240398729-A1 Methods and Compositions for the Treatment of Cytoplasmic Glycogen Storage Disorders DUKE UNIVERSITY (US) 2024-12-05 US claimed
EP-4463485-A2 TETRAHEDRAL ANTIBODIES Biomolecular Holdings LLC (US) 2024-11-20 EP claimed
EP-4329849-A1 INHALER 3D Engineering Design Limited (GB) 2024-03-06 EP claimed
WO-2023192319-A1 CHEMOKINE RECEPTORS AND ALPHA1 ADRENERGIC RECEPTORS/VASOPRESSIN RECEPTORS 1A HETEROMERS AS DRUG TARGETS FOR DISEASE UNIVERSITY OF SOUTH FLORIDA (US) 2023-10-05 WO claimed
WO-2023137387-A2 TETRAHEDRAL ANTIBODIES BIOMOLECULAR HOLDINGS LLC (US) 2023-07-20 WO claimed
WO-2023137373-A1 TETRAHEDRAL ANTIBODIES BIOMOLECULAR HOLDINGS LLC (US) 2023-07-20 WO claimed
US-20230220116-A1 TETRAHEDRAL ANTIBODIES BIOMOLECULAR HOLDINGS LLC (US) 2023-07-13 US claimed
US-5626854-A XANTHINE OR B-ADRENERGIC STIMULANT KAO CORPORATION (JP) 1997-05-06 US claimed
EP-0508653-B1 Sustained-release pharmaceutical preparation and process for preparing the same TANABE SEIYAKU CO (JP) 1996-01-24 EP claimed
US-5474783-A In the form of sheet; used for applying to the dermis NOVEN PHARMACEUTICALS, INC. (US) 1995-12-12 US claimed
EP-0424168-B1 POLYMER COMPLEXES OF A SUGAR RESPONSE TYPE NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1993-09-01 EP claimed
EP-0424168-A1 Polymer complexes of a sugar response type NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-04-24 EP claimed
EP-0232569-B1 1-BENZYL-2-(N-SUBSTITUTED)-CARBAMOYL-TETRAHYDROISOQUINOLINES AND METHOD FOR THE PREPARATION THEREOF T P O "PHARMACHIM" (BG) 1990-03-14 EP claimed
EP-0167204-B1 METHOD FOR IMPROVING THE ABSORPTION AND EFFECTIVENESS OF A CATECHOLAMINE COMPOUND SIMES S.p.A. Società Italiana Medicinali e Sintetici (IT) 1989-09-27 EP claimed
EP-0190449-B1 ADDITIVE-CONTAINING PAINTS OECE Industrie Chimiche Spa (IT) 1989-08-09 EP claimed
US-4778673-A THERAPEUTIC OR PROPHYLACTIC ACTION TO PREVENT OR NEUTRALIZE IRRITATION OF RESPIRATORY TRACT MUCOSAE; TERPENES; ODORS OECE INDUSTRIE CHIMICHE SPA (IT) 1988-10-18 US claimed
EP-0190449-A1 Additive-containing paints OECE Industrie Chimiche Spa (IT) 1986-08-13 EP claimed